The innovative agitation and aeration system is designed to reduce cellular damage and shorten mixing times by ensuring optimal mixing and a more homogeneous distribution of nutrients, gases, and additives. This results in increased yield and improved quality of the final product.
The project targets the development of an optimized system to enhance lentiviral vector productivity from suspension HEK293T cell cultures. In parallel, the lentiviral production protocol will be further optimized to fully leverage the performance improvements enabled by the advanced agitation and aeration technology.
This project is funded by the Spanish Ministry of Science and Innovation and represents an extension of previous international R&D initiatives developed by the company.